On Monday, the pair released the trailer promoting The Me You Can't See, which premieres on Apple TV+ on May 21.
"All over the world people are in some kind of mental, psychological, emotional pain," Oprah says as she sits opposite Harry discussing mental health. "Being able to say, 'This is what happened what happened to me,' is crucial," she adds.
Harry — who has spoken of his own challenges, especially in the wake of the death of his mother Princess Diana in 1997 — says, "To make that decision to receive help is not a sign of weakness. In today's world, more than ever, it is a sign of strength."
Watch: Trailer - The Me You Can't See
Poignantly, as the then 12-year-old Harry is shown alongside his father Prince Charles solemnly standing to attention as his mother's casket passes on the day of the funeral, a voiceover says, "Treating people with dignity is the first act."
Meghan Markle — in a "Raising the Future" T-shirt — also makes a cameo in the trailer, smiling and looking over Harry's shoulder as he works at his laptop.
REX/Shutterstock; Wiktor Szymanowicz/Barcroft Media Prince Harry and Oprah Winfrey
VALERIE MACON/AFP/Getty Prince Harry
"The results of this year will be felt for decades," adds Harry as a photo of Meghan reading to their son Archie is shown. "By kids, families, husbands, wives – everybody."
Glimpses of the series' interviewees, from Glenn Close to Lady Gaga, are also unveiled. "I don't tell this story for my own self-service. I've been through it and people need help," Lady Gaga, who is identified by her given name, Stefani, says in the clip.
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Courtesy of Apple The Me You Can't See promo
The trailer comes a few days after Harry appeared in a new episode of Dax Shepard's Armchair Expert podcast, in which the Duke of Sussex shared some never-before-heard stories about the pressures of growing up royal, the importance of therapy and the early days of his relationship with Meghan.
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