'Promising Young Woman' Blu-ray featurette exclusive
Writer/director Emerald Fennell and stars Carey Mulligan, Alison Brie, and Laverne Cox discuss how the film explores the gray areas still surrounding society's approach to consent.
Few pre-pandemic rules and practices are back in place at the moment, but things are slowly returning. One of the most missed is the samples at Costco — but eagle-eyed fans have spotted them in stores recently…with a bit of a twist.With mask rules still in place in all Costco warehouses, samples appear to be now placed in small, white to-go bags for shoppers to enjoy once they are out of the store. Instagram account @costcodeals posted about the spotting at a location in Aloha, Ore. There is a sign on the sample table that says they are carry out only, and should not be eaten inside. (Related: Costco Foods You Should Always Avoid, According to Nutritionists.) View this post on Instagram A post shared by COSTCO DEALS (@costcodeals)Fans are excited, regardless of the presentation and the new rule. One commenter called it a brilliant idea and mentioned how they miss the samples because it encouraged them to buy things they never would have before. Another simply called it "Beautiful," while another said, "Nature is healing! Samples are back!" Others are not so sure the rule of no eating will be followed, and say they won't be grabbing a bag of their own.So far Costco has not given any updates on this COVID-19 rule, but samples aren't the only familiar things you'll see back at your local warehouse soon. Here are the 10 Popular Products Coming Back To Costco This Year.And to get all the latest Costco news delivered right to your email inbox every single day, sign up for our newsletter!
Four months into the largest U.S. vaccine rollout in decades, it's become clear that the messaging surrounding COVID-19 vaccination efforts is as important as the science behind them.That was true when the first COVID vaccines were introduced in December at hospitals and nursing homes and even more so after the federal government on Tuesday paused the Johnson&Johnson vaccine after reports of extremely rare but very serious — in one case, fatal — side effects emerged.Most health experts largely applauded the government for its decision, saying it showed regulators making vaccine safety their top priority. They said regulators need to strike a balance between addressing small but serious risks while encouraging millions to get inoculated to quickly end the pandemic."The pause is a good decision and shows the public health system is working," said Noel Brewer, a professor in the health behavior department at the University of North Carolina-Chapel Hill. Read on—and to ensure your health and the health of others, don't miss this urgent news: Here's How You Can Catch COVID Even If You're Vaccinated. 1 What Exactly Happened With the J&J Single Shot Anyway? The Centers for Disease Control and Prevention and the Food and Drug Administration recommended Tuesday that health providers and states temporarily stop the use of J&J's COVID vaccine after reports emerged that six women in the U.S. who got the single-shot preventive developed a rare but serious blood clot. One of the women died and another is in critical condition.All six cases occurred among women between the ages of 18 and 48, and symptoms occurred six to 13 days after vaccination, FDA and CDC officials said.It's the latest in a series of messaging challenges.This pause comes less than a week after three vaccine clinics in Georgia, North Carolina and Colorado temporarily stopped using the vaccine when several people fainted or became dizzy immediately following their shots. Fainting is a known risk from all vaccines, affecting about 1 in 1,000 people, health experts say. In response to these cases, some health experts questioned whether even the short-term halt was necessary.In addition, federal regulators are concerned that the blood clotting seen with the J&J vaccine is the same type as seen globally with AstraZeneca's vaccine. The AstraZeneca vaccine isn't in use in the United States but has been authorized in more than 70 countries. The European Medicines Agency recently concluded that unusual blood clots with low blood platelets should be listed as "very rare side effects" on the AstraZeneca vaccine label. While advising the public to look out for signs of clots, the European regulators said the benefits of the shot were still worth the risk.It also comes on the heels of questions faced by J&J regarding its rollout after a Baltimore subcontractor who was making its vaccine accidentally spoiled 15 million doses earlier in April. The problems at the facility were contributing to a drop in J&J doses this month. 2 But What Does All This Mean in Terms of My Risk? More than 560,000 Americans have died of COVID in the past year — or 1 in 586 people. An individual's risk of dying of or being hospitalized with COVID is far higher than the risk of getting a rare blood clot from the J&J vaccine.Meanwhile, the risk of getting a blood clot is also far higher if you have COVID.To put the less-than-1-in-a-million risk of getting a severe blood clot from the J&J vaccine in perspective, people face a 1-in-500,000 chance each year of being struck by lightning."It's important to keep these numbers in context," Jonathan Watanabe, a pharmacist and an associate dean in the College of Health and Sciences at the University of California-Irvine, said of the rare blood clots. "While frightening, it's a rare event." The risk of blood clots associated with COVID infection is actually greater, he added.The pause, which FDA officials said they expect will be a few days, will give regulators time to alert doctors to the added risk and show them how to recognize and treat the clots and make reports to the government.The CDC will convene a meeting of the Advisory Committee on Immunization Practices today to further review these cases and assess their potential significance. The committee could recommend adding the blood clot risk to the list of warnings about the vaccine or could recommend that certain populations avoid the vaccine.RELATED: Most COVID Patients Did This Before Getting Sick 3 Why Is Messaging Important? How the concerns about risk are communicated could have a lasting impact on whether some people go ahead and get vaccinated."The messaging is very important because science alone does not get us to the outcomes we need," said Zoë McLaren, associate professor in the School of Public Policy at the University of Maryland-Baltimore County.McLaren said the FDA is known for being risk averse and that's how it developed its reputation for protecting Americans' food and drug supply. "Part of messaging is communicating to the public what the FDA is doing," said McLaren, who was inoculated with the J&J vaccine.J&J's is one of three COVID vaccines that have been cleared for use under an emergency authorization in the U.S. Unlike the Pfizer and Moderna vaccines, which require two doses, the J&J version requires only one shot.According to the CDC's vaccine tracker, nearly half of U.S. adults have been at least partially vaccinated, and the numbers have been soaring in recent weeks to an average topping 3 million doses a day.Of the more than 190 million doses of COVID vaccine administered in the U.S., about 7 million were J&J.Nonetheless, the number of new COVID infections is still rising in many states and there are concerns from CDC Director Rochelle Walensky and others about another surge as a result — in part — of people hesitating to get vaccinated.On the bright side, though, the blood clot issue comes months after the vaccination rollout began and as Moderna and Pfizer have committed to having enough doses to vaccinate most Americans.RELATED: 35 Places You're Most Likely to Catch COVID 4 How Does This Play Into Vaccine Hesitancy? Does Transparency Help or Hurt? The latest surveys show 13% of adults say they won't get a COVID vaccine and 15% will get one only if required by their employer or to travel.Experts are torn on whether the J&J pause will increase hesitancy among some people or give them more confidence in how federal regulators are overseeing the vaccination effort.Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security, said he worries the pause will have a lasting effect. "We have a lot of vaccine hesitancy that exists, and that is only going to be magnified."But to Dr. Kartik Cherabuddi, an infectious-disease specialist at the University of Florida health system, this is one hurdle in the long vaccination game. He predicts the overall effect from the pause will be minimal within a few weeks as regulators and health providers put the vaccine risks in perspective for the public. He said Americans are used to being told about the health risks of drugs, as they are bombarded with television drug advertising.Meanwhile, UC-Irvine's Watanabe said he hopes the pause will lead to more discussions with hesitant Americans about how they have several vaccine options. Watanabe said it was wise of the FDA to show "an abundance of caution" by pausing use of the J&J vaccine now, particularly because there are two other vaccine options for Americans that can more than fill the gap. And to get through this pandemic at your healthiest, don't miss these Sure Signs You've Already Had Coronavirus.This article had been published in Kaiser News. KHN (Kaiser Health News) is a national newsroom that produces in-depth journalism about health issues. Together with Policy Analysis and Polling, KHN is one of the three major operating programs at KFF (Kaiser Family Foundation). KFF is an endowed nonprofit organization providing information on health issues to the nation.
The best recent crime and thrillers – review roundup. The Khan by Saima Mir; Tall Bones by Anna Bailey; Greenwich Park by Katherine Faulkner; The Girls Are All So Nice Here by Laurie Elizabeth Flynn; and Bullet Train by Kotaro Isaka
In a season with non-stop announcements about new alcoholic drinks to try, a new study has made an important discovery on how drinking can affect our brains. This understanding casts the function of the brain in a new light when it comes to processing alcohol, and may lead to more modern methods for treating people who have alcohol dependence.For the study, which was just published in the journal Nature Metabolism, researchers at the University of Maryland School of Medicine partnered with the National Institute on Alcohol Abuse and Alcoholism to examine how the brain plays into metabolizing alcohol.Of course, it's well-known that the liver is considered the key organ in the body's ability to process alcohol. The liver breaks alcohol down into compounds, creating one called acetaldehyde, which has been known to produce the impaired speech, motor skills, and reasoning an individual exhibits when considered "drunk." Acetaldehyde then turns into acetate, which the researchers refer to as a "benign substance" that wasn't previously thought to be much of a factor in creating these sedative effects.RELATED: The One Vitamin Doctors Are Urging Everyone To Take Right NowUsing MRI scans for both humans and mice, the researchers discovered ALDH2, an enzyme that converts acetaldehyde into acetate within the brain. It showed up in the cerebellum (which controls balance and coordination), as well as the hippocampus, amygdala, and prefrontal cortex—all areas of the brain that play a role in decision-making and regulating emotions. When the ALDH2 enzyme was singularly removed, the researchers stated that the "the mice were resistant to motor impairment inducted by alcohol consumption."Eat This, Not That! Medical Expert Board member Howard Grossman, M.D. helps us understand the significance of the findings. "It seems important because it has long been felt that the metabolites of alcohol from the liver were what cause the effects of alcohol," Grossman says. "But now they find that alcohol actually works directly on certain areas of the brain that control things like awareness, coordination and impulse control," and that "the metabolite acetate, felt to be benign previously, may also act differently in the brain."Grossman explains the takeaway: "If the same phenomenon exists in humans as in mice, it gives the hope of finding a way to block the effects of alcohol—both the ones we enjoy and the ones that lead to dependence. If you could keep people from feeling anything from alcohol, it might seriously impact one of the pathways to dependence and addiction."If you're looking out for your liver health, check out the 5 Popular Foods That Cause Damage to Your Liver, and sign up for the Eat This, Not That! newsletter for healthy eating and drinking news delivered to your inbox daily.
Gnome limits: UK garden centres run out after Suez blockageLack of raw materials and rise in sales over lockdown has led to shortage of garden ornamentsCoronavirus – latest updatesSee all our coronavirus coverage Garden centres have been contacting suppliers across Europe to ship more gnomes to the UK. Photograph: Paul Marriott/Rex/Shutterstock
Buckingham Palace recently announced the funeral plans.
The funeral will take place on Saturday, April 17.
Why the big bright dress will be a post-lockdown fashion staple. Loose, lightweight and perfect for dancing, voluminous frocks promise freedom from fake tan, tailoring and depilation
Buckingham Palace has revealed which members of his family will be at the funeral
Simon & Schuster refuses to distribute book by officer who shot Breonna Taylor. US publishing giant was due to distribute Jonathan Mattingly’s The Fight for Truth for rightwing outlet Post Hill Press
Undreamed Shores by Frances Larson review – the heroines of British anthropology . Adventures in Siberia, in the Nile Valley and on Easter Island ... but these female pioneers faced prejudice and tragedy at home
Dictionary of Lost Words by Pip Williams review – a gentle, hopeful storyBased on real events, this tale of the OED’s compilation explores how words take on different meanings for men and women ‘It took 40 years for the first volume to be published’ … A New English Dictionary, which became the Oxford English Dictionary. Photograph: Alamy
From snoods to Satan: this week's fashion trendsWhat’s hot and what’s not in fashion this week Not today, Satan. Photograph: Alamy
That glorious mix of chilly air and clear, bright skies? There’s a word for that Apricity is a word to savour: contrast is what makes life sing ‘Go forth, and revel in the weather.’ Photograph: Getty Images
A history of the word ‘divisive’: once admirable, now a criticismThe No 10 race report was recently called ‘divisive’ – but when was the last time we were all of one mind on a topic? Divisive is ‘something that one should never be in politics unless it is to one’s advantage’. Photograph: Addictive Stock Creatives/Alamy
Before Covid, giving up flying was taking off. We need to get that momentum backInterest in low-carbon living, including pledges not to fly, was high before the pandemic. After lockdown, we must not allow climate action to fall off the radar Train travel on the Côte d’Azur. Photograph: Alamy
Kate Walsh, 53, seriously hasn't aged in over a decade. On Thursday, the Private Practice and The Umbrella Academy star modeled a leopard bikini from one of her "fav" female founders, Ambra Fossati, whose womenswear brand Ambra Maddalena uses "recycled ocean plastic to create swimsuits and bikinis.""Ambra creates her clothes for girls who want to be conscious consumers without compromising their style aesthetic," Walsh captioned her Instagram. "Ambra's looks are all about falling in love, summer romances, femininity, creativity, and the expression of one's true self." Speaking of selves, how does the actress manage to make 53 look so good? Here are some of her best health, wellness, and fitness tips, as well as those snaps from the beach. 1 She Has Followed a High-Fat, Low-Carb Diet @katewalsh / InstagramKate told Coveteur that she relies on a high-fat and low-carb diet. "We're sort of socialized to stay away from fats in our culture, when it's actually the opposite; sugars and carbs are the ones that are bad, our brains are 60% fat. We need good fats, and the proof is in the blood work," she said. "I went and had a physical after doing a year of high fat—including animal fats—and my numbers were great. My cholesterol went down, my bone density went up, so that's really interesting. One of the positive things about the age of information is we're starting to learn a lot more about our bodies, how they work, and how our brains work. I think with brain health, you're going to see a lot more of that, in the way that we became conscious about heart health." 2 She Mixes Up Her Workouts ShutterstockWalsh, the creator of Boyfriend Perfume, switches up her workout routine, she told Coveteur. "When I'm at home in L.A., I hike with the dogs, but since I'm in New York, I do Pilates mixed with hot yoga. I do some weight training, too." 3 She Doesn't Weigh Herself Walsh at the 21st Costume Designers Guild Awards x Getty Images Portrait Studio presented by LG V40 ThinQ on February 19, 2019 / Getty ImagesKate focuses on how she feels, not the number of the scale. "I want to look a certain way and feel a certain way, and that's what I go by. I don't weigh myself, I go by how I feel in my clothes," she told Coveteur. "I think it's also important for women to be easy on themselves and be comfortable and healthy. At different times and different ages, you're different weights and different shapes. I think that's important." 4 She Drinks A Lot of Water Getty ImagesHydration is important for Walsh, and she makes sure to drink enough water with a certain trick. "Clearly [I drink a lot of water]—I bring my own water cooler. Lemon is great because the alkaline balances your body," she told Coveteur. "I feel like I'm winning if I drink one of these [jugs] a day, plus a couple more glasses. This will make you do it. It's like a giant sippy cup." 5 She Gets Her Zs "I think we're all underslept," Walsh told Simplemost, revealing that she aims for eight hours of sleep each night, and makes sure that she gets no less than six. 6 She Prioritizes Her Mental Health Photo by Ilya S. Savenok/Getty Images for Create&CultivateWalsh revealed to the Huffington Post that getting her zen on is a priority. "I meditate and I have a really great support system. I have a core group of friends that I talk to daily, and my brother and my mom. I think that community is a huge part of mental health. You need to feel connected. I think that's why it can be so painful ― for any human on the planet, but particularly for teens ― to feel isolated. Connection and feeling like you have at least one person to talk to is really imperative," she said. Speaking of community, to celebrate one of Walsh's "fav" female founders: Make sure to follow @Ambra_Maddalena on Instagram and check out AmbraMaddalena.com.
Mourning Carla Zampatti: ‘She’d say this is the best-dressed funeral she had ever attended’Australia’s fashion doyenne has been commemorated in a state funeral her children said befitted her elegant legacy Fashion designer Carla Zampatti in 2009. Some 1,200 mourners attended her state funeral in Sydney on Thursday. Photograph: Dean Lewins/AAP
And gave fans a peek at her very special stationery.
Graham Greene’s showdown with Soviet spy Kim Philby: A Splinter of Ice reviewAvailable online A meeting between the writer and the double agent, once colleagues at MI6, is strong on friendship and betrayal – but takes us no closer to the heart of either man Beautifully acted … Oliver Ford Davies as Greene, left, and Stephen Boxer as Philby. Photograph: James Findlay