The two leading teams in the division collide as Sarries look for redemption having lost last year’s final to Leicester in dramatic fashion.
The Sharks, meanwhile, are a club on an upward trajectory after a more than difficult period.
Winners for the only time back in 2006, the travelling support could witness a famous day in Sale’s history.
England team-mates George Ford and Owen Farrell meet in what looks an engrossing battle and one laced with dramatic narratives everywhere you look.
Where to watch Saracens vs Sale
TV channel: Today’s game will be broadcast live free-to-air on ITV1 in the UK, with coverage starting at 2.25pm BST ahead of a 3pm kick-off.
BT Sport 1 will also show the game live, with their coverage starting at 2pm.
Live stream: ITVX will offer a free live stream service online. BT Sport subscribers will also be able to watch via the BT Sport website and app.