The 36-year-old Argentinian actress took to Instagram with a reel showing clips of Bublé with their four children, thanking him for "doing whatever it takes to make them happy," as written in the video.
Bublé and Lopilato have four kids together: 10-year-old Noah, seven-year-old Elias, four-year-old daughter Vida and infant Cielo.
In the caption of her Father's Day post on Sunday, Lopilato called herself lucky.
"I feel incredibly fortunate to have you as my life partner and to watch you as a loving dad to our children," she wrote to the "Haven't Met You Yet" singer.
"Thank you for being the rock of our family, for always putting our kids’ needs first and for being a consistent source of love and support in their lives," she penned.
The mom said her husband was "inspiring" in the way he plays with and teaches their children. She added his love doesn't go unnoticed.
"From changing diapers to teaching them to ride a bike, every moment you spend with our children makes a difference.
Thank you for being such a wonderful father, husband, and partner.Luisana Lopilato
"I am lucky to have you by my side, and I look forward to many more years of adventure ahead with you and our amazing family."
The couple's fans rushed to Lopilato's comments with well-wishes.
"Not only is Michael is a great dad, you’re also a great mom," one person wrote. "I love how you both support each other."
"Beautiful family," a comment read, with a heart emoji.
"Beautiful words, [you're a] lucky woman to have a great dad and husband to four beautiful kids," another person added.
Last month, Lopilato shared another note to her husband saying she's proud of him.
Bublé won the Academy Award back in February for best traditional pop vocal album for his latest album, "Higher," but only unboxed his trophy at home for the first time earlier this week.
In an Instagram post, Lopilato congratulated her husband in the caption and praised him for including their son Noah in his creative process.
Bublé responded to her message in the comments, saying "You are always the inspiration, my love," translated from Spanish.